Yes, the snows of irrelevancy must fall to an extent upon us all. One of those Shakespearean realities of life in the media. We all know the lines, Buddhist truth almost, "a tale told by an idiot, full of sound and fury, signifying nothing." Joyce renders it well, poignantly, at the end of the Dubliners collection, in such terms. Perhaps it's something a writer would tend to identify with, speaking of his own work. (And any writer who does not realize this central reality is a fool, a lesser one.) Lincoln wearily realizes it in his groove, "the world will little note, nor long remember..." but still you have to say things.
Here's a good piece about Bono from the NY Times.
Chasing Relevancy at Any Cost, Even Free
For Bono and U2, Apple iTunes Partnership Finally Hits a Wrong Note